We will be closed for the UK bank holiday (26th May), orders placed after 3pm on 23rd May will be dispatched upon our return (27th).
Every shot of ION* Gut + Microbiome contains the instructions your body needs to build the foundation of your microbiome – because gut health = good health.
£17.00 – £77.00 - or subscribe
Backed by science and powered by nature, this soil-derived supplement triggers your body to begin strengthening your gut lining in as little as 16 minutes. Experience smoother digestion, better nutrient absorption and real support where it matters most, after all gut health = good health.
Unlike traditional probiotics, which introduce one or two species of bacteria into your gut, ION* Gut + Microbiome triggers your body to naturally strengthen your gut lining and support a healthy, diverse microbiome.
The triggers are communicated at a cellular level, causing your body to restore gut lining integrity, building the foundation for a healthy gut.
A healthy gut can defend against toxins, enhance digestion and support a strengthened immune system.
With no added bacteria, this glyphosate-free, easy-to-take supplement adapts to your body’s unique needs, helping you feel healthier from the inside out.
Humic extract, trace minerals, filtered water and a dash of sea salt.
Taste profile: Taste can vary from little to no taste to a slight mineral flavour.
Your gut lining is protected by microscopic seals between cells called tight junctions.
These seals help block harmful toxins while still letting nutrients through – like a smart filter for your body.
Everyday exposures like gluten and glyphosate (a chemical found in herbicides) can weaken these seals, allowing things into your bloodstream that don’t belong and letting essential nutrients leak out. ION* Gut + Microbiome triggers your body’s innate ability to strengthen and restore this intelligent barrier in just 16 minutes.
A healthy gut supports digestion, nutrient absorption and overall health.
From your very first sip of ION* Gut + Microbiome, you are building a stronger and more resilient gut, with measurable results in as little as 16 minutes.
And the benefits that follow from that one simple action?
Nothing short of remarkable.
Maintaining good gut health is essential to overall well-being because the gut does far more than digest food.
Your gut is a central hub that supports the immune system, mental health, brain performance and nutrient absorption. The lining of the gut acts as a protective barrier, allowing nutrients and water to pass through while keeping harmful bacteria and toxins out.
When your gut barrier is strong and balanced, it supports every system in the body; when it’s compromised, inflammation and illness can follow.
Around 70% of the body’s immune cells are found in the gut, meaning that a healthy digestive tract plays a direct role in defending against infection and maintaining immune balance.
A well-functioning gut microbiome – the trillions of beneficial bacteria living inside us – helps train the immune system to distinguish between harmful invaders and harmless substances, reducing the risk of chronic inflammation and autoimmune responses.
The gut has a powerful connection to the brain, often referred to as the “gut-brain axis.” This communication pathway explains why gut health affects mood, stress levels and mental clarity.
Gut bacteria produce many of the body’s neurotransmitters, including serotonin, which influences happiness and emotional stability.
When the gut is out of balance, people often experience brain fog, anxiety, or low mood, highlighting how deeply our digestion and mental health are linked.
Efficient nutrient absorption is one of the most important roles of a healthy gut. Every cell in the body depends on the vitamins, minerals, amino acids and fatty acids that come from the food we eat but these nutrients can only be used if they’re properly absorbed through the intestinal wall.
The lining of the small intestine is covered in microscopic folds called villi and microvilli, which dramatically increase the surface area available for absorption. When the gut is healthy, these structures work like a finely tuned filter, allowing nutrients to pass into the bloodstream while keeping out harmful substances.
If the gut lining becomes inflamed or damaged, by poor diet, chronic stress, medications, or toxins like glyphosate for example, this delicate system can break down.
When that happens, nutrients aren’t absorbed as efficiently, even if your diet is rich in healthy foods. Deficiencies in key nutrients such as iron, zinc, vitamin B12, magnesium and essential fatty acids can then develop, which can leave you feeling fatigued, foggy or run down. Over time, poor absorption can also weaken the immune system and affect hormone balance and brain function.
When your gut barrier is strong and functioning well, your body can fully access the nourishment it needs for energy, focus, immunity and long-term health.
A team of leading researchers studied the real impacts of ION* Gut + Microbiome from strengthening gut integrity to dramatically improving nutrient absorption to aiding gluten digestion.
It’s changing the way we view gut health.
Our intestines are lined with a protective barrier made up of “tight junctions” – tiny connections between cells that help keep harmful substances out of the bloodstream. When these junctions are disrupted, it can lead to inflammation and gut issues, such as those seen in conditions like irritable bowel syndrome.
Glyphosate, a common chemical used in weed killers, is known to interfere with this protective barrier.
An in vitro study looked at whether a natural, soil-derived supplement made from lignite (a type of ancient plant material) could help protect intestinal cells from glyphosate’s damaging effects.
Researchers grew two types of intestinal cells in the lab and measured how well their barriers held up, both with and without glyphosate, and with or without the lignite extract.
The results showed that the lignite extract helped strengthen the intestinal barrier and prevented glyphosate from breaking it down.
In other words, the supplement appeared to block the harmful effects of glyphosate on gut cell integrity. While these findings are early and based on cell studies, they suggest that the lignite-based supplement (ION* Gut + Microbiome) might one day help protect or support gut health if proven effective in human trials.
Tight junctions are tiny structures that connect the cells lining the gut and act as selective “gatekeepers,” deciding what can pass through the intestinal wall and enter the bloodstream. When these junctions work properly, they help maintain a strong, healthy gut barrier.
However, certain substances, such as gliadin, a component of gluten, are known to weaken tight junctions, allowing unwanted particles to pass through. This process can contribute to gut inflammation and sensitivities in some individuals.
This study explored whether a natural, soil-derived lignite extract supplement (known as IO* Gut + Microbiome) could help protect and strengthen these tight junctions. Researchers used laboratory models of small intestine and colon cells to test how the supplement affected barrier strength, both on its own and when exposed to gliadin. They measured tight junction function using a method called trans-epithelial electrical resistance (TEER), a standard way to assess how well cells maintain their protective barrier.
The team also tested the supplement’s safety by looking at whether it caused or reduced cell death (apoptosis) in intestinal and kidney cell cultures.
The results were promising. ION* Gut + Microbiome increased barrier strength in both small intestine and colon cells and prevented gliadin from weakening the tight junctions.
In addition, the supplement actually reduced cell death across all cell types tested, suggesting it may have protective, rather than harmful, effects. Importantly, no signs of toxicity were observed even at high concentrations.
In summary, the lignite-based supplement appeared to help maintain and protect the gut barrier from gluten-related stress in cell studies.
Over the past decade, scientists have begun to recognise that the health of the gut lining, often referred to as intestinal permeability or gut barrier integrity, plays a vital role in overall wellness. The gut isn’t just a digestive organ; it’s a complex system that interacts with the immune system, the nervous system and even the brain. When this barrier functions properly, it allows nutrients to pass through while keeping out harmful substances. But when it becomes too “leaky,” unwanted particles like toxins, microbes and undigested food can enter the bloodstream, triggering inflammation and immune responses that affect the whole body.
This gut barrier is maintained by a network of proteins called tight junctions. These microscopic structures act like intelligent gatekeepers between cells in the intestinal wall, deciding what gets absorbed and what stays out. However, tight junctions can be disrupted by certain foods and chemicals including gluten, alcohol, some medications and the herbicide glyphosate. When these junctions break down, both the gut barrier and the blood-brain barrier can become more permeable, allowing substances to pass into areas where they don’t belong and potentially contributing to inflammation, fatigue, brain fog or other health issues.
Research has also shown that a protein called zonulin plays a key role in regulating these barriers. Zonulin levels can rise in response to gluten and glyphosate exposure, temporarily opening tight junctions. Over time, frequent activation of this pathway may contribute to chronic inflammation and autoimmune diseases such as celiac disease and type 1 diabetes. Measuring zonulin in urine or blood has become an important way to assess gut barrier function in both clinical and research settings.
To better understand how to support barrier integrity, a clinical study was conducted using a natural, soil-derived humic extract supplement known as ION* Gut + Microbiome (previously Terrahydrite®). In this double-blind, placebo-controlled trial, healthy adults took either the supplement or a placebo for two weeks while continuing their normal diets. Researchers measured markers of gut permeability (including zonulin), inflammation (TNFα and IL-6), and glyphosate levels in urine samples before and after supplementation.
All participants completed the study without side effects. While both groups showed normal levels of inflammation, the supplement group showed trends toward healthier barrier function and balanced immune signaling. Previous laboratory studies had already demonstrated that ION* Gut + Microbiome strengthens tight junctions, helps protect against damage from gluten and glyphosate and supports antioxidant activity in intestinal cells. This clinical research adds to that foundation, suggesting that maintaining strong gut barrier integrity may be one of the keys to reducing inflammation and supporting whole-body health.
Drag the slider to see the difference between a strong, healthy gut lining (connected lines show tight junctions that are intact) and a gut lining compromised by toxins (gaps between cells indicate intestinal permeability).
We recommend 1 teaspoon of ION* Gut + Microbiome 3x/day. Optimal support is achieved when taken 30 minutes prior to meals, but you can take it immediately before, with, or after a meal, (or on an empty stomach) and still receive benefit.
Results can vary with initial ION* Gut + Microbiome usage, with many customers reporting rapid and profound early results. These results are not the direct effects of the supplement itself, but instead reflect the innate process that occurs in a body as the firewall system is optimally up and running. There is a subset of individuals, however, that can experience symptoms of tiredness, headache, bloating/increased gas, or bowel changes. If you feel you may be sensitive to the changes that can occur as your innate defenses and capacity for water/nutrient absorption are restored, we suggest a slower approach. Start with 1/8 teaspoon of ION* Gut + Microbiome daily, increasing usage slowly, as tolerated, to get to recommended label usage.
Currently, 86% of the population suffers from gas, bloating, indigestion, and heartburn, with a good majority stemming from poor gut health. But when you factor in inflammation that is caused by poor gut health, those are just the tip of the iceberg. Given the number of issues that chronic inflammation is responsible for, maintaining gut health is vital.
So why do we suddenly need help maintaining our gut health? To start, overprescribed antibiotics, glyphosate damage, and a lost connection with our environment. Our microbiome is not thriving as it should, and neither are we. Rather than address a specific medical condition with a narrowly-targeted supplement, ION* Gut + Microbiome takes a holistic approach and helps maintain the strength of our immune system to create an environment that supports total body and mind health.
Your intestinal membrane, composed of billions of cells, and covering two tennis courts in surface area, is completely replaced every three days. This massive rate of turnover means that if you take 1 tsp of ION* Gut + Microbiome in the morning, immediately supporting the microbiome in your gut, you have created a robust defense system against the adversity of your environment.
Humic Extract (from Ancient Soil) and Purified Water.
Our humic extract is sourced from ancient soil (roughly 60 million years old), and contains a blend of bacterial metabolites (aka, fulvate) as well as less than 1% of a variety of trace minerals and amino acids including chloride, sodium, lithium, calcium, phosphorus, sulfur, bromide, potassium, iron, antimony, zinc, copper, gold, magnesium, alanine, glycine, histidine, isoleucine, methionine, threonine, and valine.
Note: Please consult your healthcare practitioner concerning the addition or removal of probiotics and digestive enzymes in your personal regimen; as each person is unique, we cannot make individual recommendations.
ION* Gut + Microbiome is not a prebiotic, a probiotic, or a direct source of enzymes. It contains zero bacteria. We need a much more diverse microbiome than one can achieve by replicating the same strands of bacteria over and over (this monoculture can happen when we take probiotics).
ION* Gut + Microbiome is unique in that it strengthens the gut lining to foster a more diverse microbiome, naturally. A strong gut lining helps to defend against environmental and foodborne toxins that harm the microbiome, causing gut and health issues.
Please note, all of the trace minerals in our humic extract are naturally occurring, well below the RDI, and not meant to be used as supplementary to any deficiencies. The truly active compound in humic extract is the fulvate, a unique family of carbon molecules with oxygen-binding sites that are produced by bacteria when they digest nutrients. These molecules are the backbone of the ION* blend, helping with critical functions like cellular and microbial communication and chelation of nutrients.
We did not change our formula with our latest brand refresh.
We captured lightning in a bottle with Terrahydrite, the innovative and all-natural blend utilized across our entire product line. And while we have made great strides to improve messaging, package our product more sustainably, and create transparent labeling, we have no plans of altering what is actually in the bottle.